This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, laboratory work and mixing in open batch processes. Note that this does not mean that they are properly structured names according to the IUPAC nomenclature. Suspendisse porttitor leo quis purus porttitor posuere sit amet sit amet nunc. Registrants can choose from the following picklist endpoint conclusions/effect levels: This section displays the values related to sensitisation from all registered dossiers for the substance. This section summarises the dissociating values from all registered dossiers for the substance. Half-life in sediment provides substance information on the substance’s half-life in sediment in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. This section summarises the values related to phototransformation in air from all registered dossiers for the substance. Authorisation list (Annex XIV) – indicates if the substance is included in the Authorisation List. EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Select which sections to print from the substance’s Brief Profile. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment). If so, the data provided is not processed for the Brief Profile. EC10 / LC10 or NOEC for freshwater plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater plants or the no observed effect concentration for freshwater plants. 13679 Acharnes Attiki Greece, Penpet Petrochemical Trading GmbH, Merkurring 105 22143 Hamburg Germany, Pliva Hrvatska doo, Prilaz baruna FilipoviÄa 25 10000 Zagreb Croatia, POLYNT S.p.A., via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy, SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany, SIPCAM OXON SPA, Via Sempione, 195 20016 Pero Milano Italy, Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands, Tate&Lyle slovakia s.r.o.-5, Boleráz 114 91908 Boleráz 114 Portugal, TCL GLOBAL BV as ONLY REPRESENTATIVE OF THIRUMALAI CHEMICALS LIMITED, Saturnusstraat 46-62 2132 HB Hoofddorp Netherlands, Xerox (Europe) Limited, Ballycoolin Business Park Blanchardstown Dublin 15 Dublin Ireland, Xerox Manufacturing (Nederland) BV, Maasheseweg 89-91 5804 AB Venray Limburg Netherlands, Yordas GmbH, ÃuÃere Nürnberger Str. ABC corresponds to the atomic number of the most characteristic element or the most characteristic organic group in the molecule. No or insufficient data available at present, Hazard related to composition of atmosphere identified, No potential to cause toxic effects if accumulated (in higher organisms) via the food chain, bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day), DMEL (Derived Minimum Effect Level) - not included for short–term effects, Insufficient data available (further information necessary), Hazard unknown (no further information necessary), Hazard unknown but no further hazard information necessary as no exposure expected, ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added, Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian), No adverse effect observed (not irritating), Adverse effect observed (irreversible damage), mg/kg bw/day (nominal/actual dose received), See ‘Study results oral: Prioritization by test species’, mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical)), ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received), mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day), mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical)), No study available / no study available (further information necessary). Note: Registrants can also select ‘other’ as the picklist conclusion. The CLP regulatory processes identified for the Brief Profile are: The BPR (528/2012) entered into force on 1 September 2013. This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance. Its chemical formula is HO 2 CCH=CHCO 2 H. Maleic acid is the cis-isomer of butenedioic acid, whereas fumaric acid is the trans-isomer.It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, maleic acid has few applications. This section summarises the values related to endocrine disrupter testing in aquatic vertebrates from all registered dossiers for the substance. Council of Europe no. Y is the check-digit calculated in accordance with the 10-digit ISBN method. The absence of an interaction does not necessarily mean no interactions exist. The Hazard classification and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Please upgrade your Internet Explorer to a newer version. Data is generally standardised and displayed in milligram per kilo soil (dry weight). Maleic acid and fumaric acid are two isomers with vastly different physical properties and pKa values for loss of both protons. Melting / freezing point provides substance information on the melting/freezing point in °C at a pressure measured in Pa. for charge, stereo–chemical and/or isotopic information. Please note that the information provided in the free-text fields is not published in the brief profiles. disodium tetraborate EC no. Recall from Section 1.10B that there is restricted rotation around carbonâcarbon double bonds. If only waived data is available for the substance, following justifications for data-waiving can be displayed in the Brief Profile: Some endpoints are not included in the Brief Profile due to the use of free text and/or complex field(s) in the reporting of information, which cannot be easily summarised by an automatic algorithm. All the source data on which the summaries on this page are based, is provided by industry and stored in the ECHA databases. Bioaccumulation Factor (aquatic species) L/kg ww provides substance information on the substance’s bioaccumulative properties for aquatic species measured in litre per kilogram (wet weight). This section summarises the vapour pressure values from all registered dossiers for the substance. If so, the data provided is not processed for the Brief Profile. For this endpoint registrants do not provide study results that are processable for the Brief Profile. Data is generally displayed in milligrams per kilogram bodyweight per day. The key difference between maleic acid and fumaric acid is that maleic acid is the cis-isomer of butenedioic acid, whereas fumaric acid is the trans-isomer.. Maleic acid and fumaric acid are carboxylic acids.They are cis-trans isomers of each other. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. RST is the consecutive number of the substance in the series ABC. A fumarate is a salt or ester of the organic compound fumaric acid, a dicarboxylic acid. The Brief Profile summarises the non-confidential data on substances as it is held in the databases of the European Chemical Agency (ECHA), including data provided by third parties. Values are generally displayed in milligram per litre. Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C. More detailed information is available in the dossiers. The cis isomer is the less stable one of the two; the difference in heat of combustion is 22. This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only. EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre. Data is generally displayed in milligram per kilo bodyweight. Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year. Please see the registered dossiers for substance information for the following endpoints: The ’Substance identity’ section links substance identification information from all databases that are maintained by ECHA. The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. If multiple values are available, the most conservative value (the highest percentage) is displayed. According to a classification scheme(2), this estimated Koc value suggests that fumaric acid is expected to have very high mobility in soil. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Due to ongoing appeals, all registrations flagged as revoked are published as, In the case of a merge between two companies having a registration for the same substance, the higher tonnage band registration is maintained as active, and the other registration is, Stability in organic solvents and identity of relevant degradation products, Storage stability and reactivity towards container material, Environmental data (monitoring data/field studies), Additional information on environmental fate and behaviour, Skin irritation/corrosion (study results), Respiratory sensitisation (study results), Repeating dose toxicity oral/inhalation/dermal/other routes (study results), EINECS (European INventory of Existing Commercial chemical Substances) List, ELINCS (European LIst of Notified Chemical Substances) List. IUPAC names gives all the non-confidential names provided to ECHA in submissions under REACH, CLP, BPR and PIC, where indicated to be a IUPAC name. This section summarises the values related to toxicity to birds from all registered dossiers for the substance. Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. Data is generally displayed in milligrams per kilogram bodyweight per day.Prioritization by test species: See ‘Summary effect on fertility oral route’. Degradation rate constant with OH radicals provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. For readability purposes, only the pictograms, signal words and hazard statements referred to in more than 5% of the notifications under CLP are displayed. This site is not fully supported in Internet Explorer 7 (and earlier versions). Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C. This website uses cookies to ensure you get the best experience on our websites. Skin irritation/corrosion provides substance information on the substance’s irritation/corrosion effect on the skin. This section provides information on the recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product, or improper storage or handling of a hazardous product. Please be aware that as additional data is submitted to ECHA, the brief profile will also be updated to reflect the new situation. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. In this case, the preferred CAS number is displayed first. This section summarises the flash point values from all registered dossiers for the substance. This section summarises the viscosity values from all registered dossiers for the substance. Proin faucibus mollis lectus ut fermentum. No data available: testing technically not feasible. Data from all dossiers registered and the Classifications and Labelling Inventory (C&L) for the same substance are used to generate the Brief Profile. Information in the guidance on safe use section consists of recommendations by a substance registrant(s) on the proper use of the substance in various situations. Different compositions or impurity profiles often lead to different classifications. If the substance has no EC number attributed, ECHA will attribute a list number. C&L Inventory . Registrants can choose from the following picklist endpoint conclusions/effect levels: Eye irritation provides substance information on the substance’s irritation effect on the eye. BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material. Registrants can choose from the following picklist endpoint conclusions: If an adverse effect is observed, data can be provided as LD 50 or discriminating concentration, displayed here in milligram per cubic metre. It is possible that the harmonisation is introduced through an amendment to the CLP Regulation. This section displays the values related to reproductive toxicity from all registered dossiers for the substance. Applicant’s summary and conclusion – Interpretation of results. If more than one type of substance is registered, both types will be displayed. a quantity of 0.317 kg of can replace 0.453 kg of citric acid. The Agency thus cannot guarantee the correctness of the information displayed. Flash point provides substance information on the substance’s flash point at a temperature measured in °C at a pressure measured in Pascal. Maleic acid is an organic compound which is a dicarboxylic acid (molecule with two carboxyl groups).Maleic acid is the cis isomer of butenedioic acid, whereas fumaric acid is the trans isomer. Molecular Weight 116.07 . If more than one numerical result is available per endpoint, the range of results (min-max) will be presented (RANGE method). More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header. Registrants can register their substance explosiveness as: Explosiveness. Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C. Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. Short-term EC50 or LC50 for birds provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of birds in the test, generally displayed in milligram per kilo food. Displayed is the most conservative of the prioritised value(s). For e.g., fumaric acid is a trans isomer, and maleic acid is a cis isomer. It does not represent a new labelling, classification or hazard statement. The total number of non-confidential registered compositions submitted in REACH dossiers are displayed here. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. the solubility rate also increases with smaller particle size. PNEC STP, data displayed in milligram per litre. 1.3), Very insensitive substances with mass explosion hazard (Div. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Data is generally displayed in milligram per litre air. This section displays the values related to genetic toxicity from all registered dossiers for the substance. If more than one value is available, results are displayed as concatenated distinct values, ordered from most to least commonly provided, with the percentage of provided values appended. Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. InChI is an abbreviated name for IUPAC International Chemical Identifier, a chemical identifier developed and supported by the InChI Trust. This section displays the values related to repeated dose toxicity from all registered dossiers for the substance. PubChem Substance ID 24900967. 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