This section summarises the values related to long term toxicity to fish from all registered dossiers for the substance. The pKa is the pH value at which a chemical species … There is additional data available for commercial users including Adverse Effects, Contraindications, and Blackbox Warnings. 2005 Jun 1;210(2-3):223-33. Other identifiers gives any other non-name identifiers available for ths substance. Phthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. It is a dibasic acid, with pKas of 2.89 and 5.51. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Y is the check-digit calculated in accordance with the 10-digit ISBN method. Anal Bioanal Chem. Candidate List – indicates if the substance is included in the candidate list of substances of very high concern (SVHCs). Values are generally displayed in milligram per litre. This section displays the values related to immunotoxicity from all registered dossiers for the substance. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C). Manufacturers and importers can provide the following information in the registration dossier: Hazard for Air provides information on the substance’s hazard assessment conclusion related to air. disodium tetraborate EC no. Applicant’s summary and conclusion – Interpretation of results. This section summarises the values related to endocrine disrupter testing in aquatic vertebrates from all registered dossiers for the substance. PIC administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre. Data is generally displayed in milligram per kilo bodyweight. Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C. Percentage distribution in the Media displays the values attributed by the registrants to the following options: For this endpoint registrants do not provide summaries that are processable for the Brief Profile.Type of study provided, No summary exists for this scientific endpoint. V.Care Service Also, if the registrant selects ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure for the concentration value, the data provided will not be processed for the Brief Profile. the minimum numerical value associated with the highest priority picklist item. J Pharmacol Exp Ther. Autoflammability / Self-ignition at 101 325 Pa provides substance information on the substance’s self-ignition temperature in °C at a pressure of 101 325 Pa. organic acids – sorted by formula Registrants can register their substance flammability as: Note: Registrants can also select ‘other’ as the flammability value for their substance. Dissociating Properties provides substance information by picklist values: Dissociation Constant provides numerical substance information on the substance’s dissociation constant values at a temperature measured in °C. This section summarises the boiling point values from all registered dossiers for the substance. Nulla pulvinar vitae nunc vitae sagittis. Half-life in soil provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C. Hazard to aquatic organisms provides information on the substance’s hazard assessment conclusion regarding aquatic organisms. test not applicable because organic peroxide. Registrants can identify the origin of their substance as being: If more than one type of substance is registered, both types will be displayed. If so, the pressure data provided is not processed for the Brief Profile. Furthermore, updates in the source data may not always result in an update of the Brief Profile. Epub 2003 Oct 25. References 1. Guidance on the safe use of the substance provided by manufacturers and importers of this substance. Definitions of the acid dissociation constant and pKa are given below the figures, together with the definition of some classes of organic acids. Proin faucibus mollis lectus ut fermentum. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. ECHA has no public registered data indicating whether or into which articles the substance might have been processed. Nam ante ipsum, suscipit non sapien nec, congue consequat ante. Based on given acidity constants (pK a values) the pH of organic acids for 1, 10, and 100 mmol/L are calculated.The results are listed in the following tables (valid for standard conditions 25°C, 1 atm):. This section summarises the values related to adsorption/desorption from all registered dossiers for the substance. The use information is displayed per relevant life cycle stage of the substance. Thirdly the display of data is prioritised by units. [, Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. See ‘Summary effect on fertility oral route’, except: This section displays the values related to neurotoxicity from all registered dossiers for the substance. Therefore the quality of these names may be variable. A recent food safety concern has arisen from the unapproved use of certain phthalates in a broad range of food/nutraceutical ingredients from Taiwan [53]. Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions: Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population). Additives are the constituents which have been intentionally added during the manufacturing process to stabilise the substance. If so, the data provided is not processed for the Brief Profile. Oral route provides substance information on the substance’s acute toxicity via the oral route. The Agency does not take any responsibility whatsoever for any copyright or other infringements that may be caused by using the information. The number of studies provided is indicated by ‘[x] studies submitted’, while the actual number of studies processed for the endpoint is indicated by ‘[x] studies processed’. See ‘Summary oral systemic effects’, except: ‘See Summary inhalation systemic effects’. Get your answers by asking now. BOD5*100/ThOD provides substance information on the substance’s BOD5*100/ThOD values displayed in O2 (milli)gram per gram test material. Data is generally standardised and displayed in in milligram per kilo of food. U.S. Patent US4734239, issued April, 1941. Duis pulvinar non magna ac viverra. Epub 2013 Jul 11. Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure. Analytical Chemistry 1959 , 31 (8) , 1326-1331. 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