0000003222 00000 n Maleic Acid is commonly used in research studies to induce Fanconi syndrome in rats and dogs in an attempt to study the mechanism of this disease. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Final report on the safety assessment of malic acid and sodium malate. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. ýWEw×¹G9®kíÙféx|m-9ÃÆdÊUIYjM¦ûõΧPnéxà%Ôìf3ç(ÊðDL èwÙ.°dÖ¶Wò6æ5ÒÛ¾ ** ÞÓÿÆ©8´ù¦iÁ_'è²î¨¦^V±E }Ûåqî¼#0bØMfÔ|ÕQ³%rãYø¬¾"QìfEM1K^ Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. Molecular Weight 138.05 . 29 0 obj<> endobj Special Hazards of Combustion Products: Irritating smoke containing maleic anhydride may form in fire. 0000001457 00000 n PubChem Substance ID 24897040 H315 Causes skin irritation. DL-Malic acid 6915-15-7 230-022-8 - - 4. 0000002662 00000 n 0000008621 00000 n endstream endobj 30 0 obj<. Maleic acid (MA) is a dicarboxylic acid that undergoes esterification with ethanol in the presence of cation-exchange resin catalysts to form diethyl maleate. Int J Toxicol 2001;20 Suppl 1:47-55. Consult a physician. Gardner WH. Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. 0000002584 00000 n startxref H318 Causes serious eye damage. 0000002901 00000 n 0 Manufacturer and Substance Identification Thirumalai Chemicals Limited, 25-A SIPCOT Industrial Complex, Ranipet, 632 403. MDL number MFCD00070246. OSHA Vacated PELs: Maleic acid: No OSHA Vacated PELs are listed for this chemical. (USCG, 1999) Maleic Acid CAS No 110-16-7 MATERIAL SAFETY DATA SHEET SDS/MSDS Signal word Warning Hazard statement(s) H302 Harmful if swallowed. 0000000790 00000 n 0000001060 00000 n 32 0 obj<>stream * Breathing Maleic Acidcan irritate the nose, throat and lungs causing coughing, wheezing and/or shortness of breath. This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) EC Number 221-461-6. Malic acid is also produced commercially and added to … Containers of Maleic Acid may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the … 0000012142 00000 n However, there's some concern that intake of malic acid may trigger certain side effects such as headaches, diarrhea, nausea, and allergic reactions. Show this safety data sheet to the doctor in attendance.Move out of dangerous area. 0000001278 00000 n 0000005262 00000 n Maleic anhydride rapidly hydrolyzes to form maleic acid in the presence of water and hence environmental exposures to maleic anhydride itself are unlikely. Hazard classification & labelling Hazard classification and labelling. 0000003146 00000 n Maleic anhydride is used in the formulation of resins. Tamil Nadu, India. If inhaled If breathed in, move person into fresh air. Its chemical formula is HO2CCH=CHCO2H. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Linear Formula C 4 H 3 O 4 Na . trailer Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. 0000006642 00000 n Physical: Maleic anhydride released into the atmosphere will degrade by reaction with ozone and photochemically produced hydroxyl radical (estimated half-life 1.7 hr). 0000007282 00000 n 0000005970 00000 n Safety Data Sheet Malic acid Revision 8 19/01/2015 - EN CAS N° 6915-15-7 EC N° 230-022-8 Pictograms: WARNING Hazard statement: H319: Causes serious eye irritation. It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, maleic acid has few applications. %%EOF Its crystalline structure has been analyzed. 0000001626 00000 n 29 24 Environmental: Maleic anhydride's fate in soil is unknown. Maleic anhydride is a low hazard profile chemical. If not breathing, give artificial respiration. Product Use: For educational use only Manufacturer: Columbus Chemical Industries, Inc., Columbus, WI 53925. Maleic acid is the cis-isomer of butenedioic acid, whereas fumaric acid is the trans-isomer. Synonym: (2)-Butenedioic acid (2Z); (Z)-Butenedioic Acid Chemical Name: Maleic Acid Chemical Formula: C4H4O4 Fiume, Z. * Contact can severely irritate and burn the skin and eyes with possible eye damage. One such study found decreased glomerular filtration rate in rats given 9.0 mmol/kg, but not with 1.5 mmol/kg, Maleic Acid intraperitoneally. Safety Data Sheet Malic acid Revision 7 01/12/2014 - EN CAS N° 6915-15-7 EC N° 230-022-8 Pictograms: WARNING Hazard statement: H319: Causes serious eye irritation. ÂW;,Úé¦óm½Ç mοïþûkX¢!s½»÷ð~£3?Þ¡q ×ÉÄMãÆc@¯vrhÎ;>CÃ7n¿jÙßß±}m{÷æ¯eV¦ßêÙ×ð{ïþÁ.úx-/òúÀGððá}ÿ`5kST+ìF§8ªsDµá }0~4üôþ§ ø¤Z¬²åõ7ÎÆÞ¸K\¼ûpÿ@ÿøÚLa°OHøÑQ³¡õ =Í.E,ï90ÿ¡5»O©ùs©ÇÂï¤Ç¯19ä{øàS þr§¯òì¶ôy¶Ì¿é~ìÜLSGfÂÁn 5$æÅ+ùÓhñG¤n'þ`æ«ÙÉ ìîÊ»ß$}ï=dÀh,jBo³´Ùÿé½38õâ÷ÃM#Þpof%åXúëe;Nï¦ø¨pp:EfýÃlG(ï³Xÿì©éçLå©àÝo¾»;ä@mÓ¿BàÜÝC#¶12ïHB85êJ*vÙúÿ. There is no reason to expect this ingredient to induce any toxicity when used for this purpose. xref View abstract. The safety of Maleic Acid as a pH adjustor should not be based on the concentration of use, but on the amount of free Maleic Acid that remains after neutralizing the formulation. Hence environmental exposures to maleic anhydride is a low hazard profile Chemical # 437.00 Section 1: and... Produced or used acid has few applications of eyes, skin and with! Manufacturing facilities spread across Western India and world wide contacts and toll manufacturers into air! 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